Android :: Efficient Way To Make Database Query Faster ?

In my android app i need to get 50,000 database entry(text) and compare them with a value when the activity started(in onCreate()).I am doing this with the simplest way : i get the whole table from db to a cursor.However this way is too laggy.Are there any other way to do it more effective?The app is "scrabble solver" that is why i am not using WHERE close in my query (Take the whole data annd compare it with combination of the input letters).At first i was using a big table which contains whole possible words.Now i am using 26 tables.This reduced the lag and i am making database call on a thread that solved a lot problems too.It is still little bit laggy but much better.